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TERM: 2021-22 Winter
COURSE NUMBER: CHEM 401
COURSE TITLE: Biochemistry II
NAME OF INSTRUCTOR: Dr. Annerieke Wolmarans
CREDIT WEIGHT AND WEEKLY TIME DISTRIBUTION: credits 3 (hrs lect 3 - hrs sem 0 - hrs lab 0)
CALENDAR DESCRIPTION: This course is a continuation of BIOL 470. The topics covered include electron transport and oxidative phosphorylation, lipids and lipid metabolism, amino acid metabolism, nucleic acids and their metabolism, photosynthesis, the chemical structure of genes and chromosomes, protein synthesis, and the structure and function of biological membranes.

Same as BIOL 471.

Prerequisites: BIOL 470
REQUIRED TEXTS: Berg, Tymoczko, Stryer, Biochemistry loose leaf. 9th edition; 8th or 7th editions acceptable ISBN: 9781319114800, Mandatory
MARK DISTRIBUTION IN PERCENT:
Attendance/Participation 2%
Quizzes 8%
Assignments 10%
Presentation 12%
Midterm Exam 1 17%
Midterm Exam 2 17%
Midterm Exam 3 17%
Final Exam 17%
100%
COURSE OBJECTIVES: At the end of this course, students will be able to:
  • Describe the process of the citric acid cycle.
  • Explain oxidative phosphorylation and its role in cellular metabolism.
  • Understand both the light-dependent and the light-independent components of photosynthesis.
  • Understand the central carbon metabolic pathways such as the pentose phosphate pathway and glycogen metabolism.
  • Explain the metabolism of fatty acids, amino acids, and nucleic acids, and how those metabolic processes are related to central carbon metabolism.
COURSE OUTLINE:
  • Unit 1
    • Glycolysis/Gluconeogenesis (regulation)
    • Citric Acid Cycle
    • Oxidative Phosphorylation
  • Unit 2
    • Glycogen Metabolism
    • Fatty Acid Metabolism
    • Light Reactions
  • Unit 3
    • Calvin Cycle
    • Pentose Phosphate Pathway
    • Protein Turnover and Amino Acid Catabolism 
  • Unit 4
    • Lipids and Steroids
    • Integration of Metabolism 
  • Unit 5
    • DNA Replication, Repair, and Recombination
    • RNA Synthesis and Processing
    • Protein Synthesis


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