TKUC LogoTHE KING'S UNIVERSITY

TERM: 2021-22 Fall
COURSE NUMBER: CHEM 400
COURSE TITLE: Biochemistry I
NAME OF INSTRUCTOR: Dr Annerieke Wolmarans (lecture), Dr Rebecca Mercier (lab)
CREDIT WEIGHT AND WEEKLY TIME DISTRIBUTION: credits 3 (hrs lect 3 - hrs sem 0 - hrs lab 3)
CALENDAR DESCRIPTION: This course is designed to introduce students to biochemistry. The focus of the lectures is on the structure and function of the chemical constituents of living organisms. The lectures cover such topics as the energetics of biochemical reactions, amino acids and peptides, protein structure and function, enzyme kinetics, bioenergetics, carbohydrates and carbohydrate metabolism.

Same as BIOL 470.

Prerequisites: CHEM 351
REQUIRED MATERIALS:
  • Berg J.M., Tymoczko J.L., Stryer L., Biochemistry - Looseleaf. 9th ISBN: 9781319114800, Optional, Helpful to Complete Assignments
  • Lab coat and safety glasses (available from The King’s University bookstore)
  • Notebook
  • Sharpie pen (fine tip)
  • Calculator
  • Laptop (when instructed)
  • Laboratory manual (only available on Moodle): Biol 470/Chem 400, Biochemistry I, Laboratory Manual 2021, The King’s University
MARK DISTRIBUTION IN PERCENT:
Assignments 12%
Midterm I 20%
Midterm II 20%
Final Exam 20%
Reflections 4%
Attendance/Participation 2%
Laboratory Mark 22%
100%
COURSE OBJECTIVES: It is the aim of the course that students acquire the following skills:
  • Understand the chemistry of important biological macromolecules.
  • Understand the principles of enzymatic activities and analysis.
  • Comprehend various metabolic pathways and appreciate its complexity, network and proper regulation.
  • Apply basic techniques used in biochemistry, then analyze and interpret biochemical data to arrive to a conclusion.
LECTURE OUTLINE:
  • Nucleic Acids
  • Amino Acids - Protein Composition and Structure
  • Exploring Proteins and Proteomics
  • Hemoglobin
  • Enzymes: Basic Concepts
  • Enzyme Kinetics
  • Enzyme Catalytic Strategies
  • Enzyme Regulatory Strategies
  • Carbohydrates
  • Lipids
  • Cell Membranes
  • Membrane Channels and Pumps
  • Metabolism: Basic Concepts and Design
  • Glycolysis & Gluconeogenesis


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