| COURSE NUMBER: |
CHEM 351 |
| COURSE TITLE: |
Organic Chemistry II |
| NAME OF INSTRUCTOR: |
Course Instructor: Dr. Leah Martin-Visscher
Laboratory Instructors: Dr. Heather Starke
|
| CREDIT WEIGHT AND WEEKLY TIME DISTRIBUTION: |
credits 3(hrs lect 3 - hrs sem 0 - hrs lab 3) |
| COURSE DESCRIPTION: |
A continuation of CHEM 350.
Prerequisites: CHEM 350 |
| COURE MATERIALS: |
- John McMurry, Organic Chemistry (9th ed), Boston: Brooks Cole, 2016
- Organic Chemistry Flashware
- C. Slupsky, H. Starke and L. Martin-Visscher, The King's University: Chemistry 350 Laboratory Experiments (2017 ed)
- Safety glasses, 2 hardcover notebooks, set of molecular models
|
| MARK DISTRIBUTION IN PERCENT: |
|
| Laboratory |
25% |
| Exam 1 | 15% | | Exam 2 | 15% |
| Final Exam |
25% |
| Quizzes & Homework |
20% |
|
100% |
|
| COURSE OBJECTIVES: |
- To
develop understanding and appreciation
for the importance of organic
chemistry and the ubiquitous nature of carbon compounds in everyday life.
- To understand the fundamental relationship between molecular structure and chemical reactivity.
- To
find patterns in the many reactions of carbon compounds by thoroughly
understanding a set of reaction mechanisms and
the patterns of reactivity of
functional groups, and employing basic
synthetic strategies. This semester, we will explore the chemistry of
aromatic compounds, alcohols (and thiols), amines, and carbonyl
containing compounds. We will end by looking at the chemistry of
important biomolecules, such as carbohydrates and proteins.
- To develop basic
competence and confidence in the
use of organic laboratory techniques of
synthesis, separation and characterization.
- To
gain expertise in the hands-on use
of modern spectroscopic tools for
determination of molecular structure, including NMR, IR, and
GC-MS.
- To be aware of the historical contexts, developments,
and philosophical presuppositions that have given rise to modern
organic chemistry.
- To be aware of
the professional responsibility of
chemists for the materials they
make, and to make conscious ethical choices about their
potential uses and abuses.
- To encourage positive, constructive interaction and collaboration amongst students and between students and instructors.
|
| LECTURE OUTLINE: |
- Structure: 1 H - NMR Spectroscopy and Mass Spectrometry
- Benzene & Aromaticity
- Electrophilic Aromatic Substitution
- Alcohols & Phenols
- Ethers & Epoxides, Thiols & Sulfides
- Aldehydes and Ketones, NAACC
- Carboxylic Acids and Derivatives
- Nucleophilic Acyl Substitution
- Carbonyl a-Substitution Reactions
- Carbonyl Condensation Reactions
- Amines
- Biomolecules: Carbohydrates
- Biomolecules: Proteins
|
| LAB OUTLINE: | - Qualitative Organic Analysis of an Unknown – Week 1
- Qualitative Organic Analysis of an Unknown – Week 2
- Oxidation of Cyclohexanol with Household Bleach – Week 1
- Oxidation of Cyclohexanol with Household Bleach – Week 2
- Grignard Synthesis of Triphenylmethanol – Week 1
- Grignard Synthesis of Triphenylmethanol – Week 2
- Chemical Literature Project
- Synthesis of 4-Phenylbenzoic Acid via Suzuki-Miyaura Cross-Coupling – Week 1
- Synthesis of 4-Phenylbenzoic Acid – Week 2
- Synthesis of 4-Phenylbenzoic Acid – Week 3
- Proteins and Carbohydrates: Isolation of Casein and Lactose from Milk
- Laboratory Clean-Up and Check-Out
|
