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COURSE TITLE: Organic Chemistry II
NAME OF INSTRUCTOR: Course Instructor: Dr. Leah Martin-Visscher
Laboratory Instructors: Dr. Heather Starke
CREDIT WEIGHT AND WEEKLY TIME DISTRIBUTION: credits 3(hrs lect 3 - hrs sem 0 - hrs lab 3)
COURSE DESCRIPTION: A continuation of CHEM 350.

Prerequisites: CHEM 350
  • John McMurry, Organic Chemistry (9th ed), Boston: Brooks Cole, 2016
  • Organic Chemistry Flashware
  • C. Slupsky, H. Starke and L. Martin-Visscher, The King's University: Chemistry 350 Laboratory Experiments (2017 ed)
  • Safety glasses, 2 hardcover notebooks, set of molecular models
Laboratory 25%
Exam 115%
Exam 215%
Final Exam 25%
Quizzes & Homework 20%
  • To  develop  understanding  and  appreciation  for  the  importance  of  organic  chemistry  and  the ubiquitous nature of carbon compounds in everyday life.
  • To understand the fundamental relationship between molecular structure and chemical reactivity.
  • To find patterns in the many reactions of carbon compounds by thoroughly understanding a set of reaction  mechanisms and  the  patterns  of  reactivity  of  functional  groups,  and  employing  basic synthetic strategies. This semester, we will explore the chemistry of aromatic compounds, alcohols (and thiols), amines, and carbonyl containing compounds. We will end by looking at the chemistry of important biomolecules, such as carbohydrates and proteins.  
  • To  develop  basic  competence  and  confidence  in  the  use  of  organic  laboratory  techniques  of synthesis, separation and characterization.
  • To  gain  expertise  in  the  hands-on  use  of  modern  spectroscopic  tools  for  determination  of molecular structure, including NMR, IR, and GC-MS.
  • To be aware of the historical contexts, developments, and philosophical presuppositions that have given rise to modern organic chemistry.
  • To  be  aware  of  the  professional  responsibility  of  chemists  for  the  materials  they  make,  and  to make conscious ethical choices about their potential uses and abuses.
  • To encourage positive, constructive interaction and collaboration amongst students and between students and instructors.
  • Structure: 1 H - NMR Spectroscopy and Mass Spectrometry
  • Benzene & Aromaticity
  • Electrophilic Aromatic Substitution
  • Alcohols & Phenols
  • Ethers & Epoxides, Thiols & Sulfides
  • Aldehydes and Ketones, NAACC
  • Carboxylic Acids and Derivatives
  • Nucleophilic Acyl Substitution
  • Carbonyl a-Substitution Reactions
  • Carbonyl Condensation Reactions
  • Amines
  • Biomolecules: Carbohydrates
  • Biomolecules: Proteins
  • Qualitative Organic Analysis of an Unknown – Week 1
  • Qualitative Organic Analysis of an Unknown – Week 2
  • Oxidation of Cyclohexanol with Household Bleach – Week 1
  • Oxidation of Cyclohexanol with Household Bleach – Week 2
  • Grignard Synthesis of Triphenylmethanol – Week 1
  • Grignard Synthesis of Triphenylmethanol – Week 2
  • Chemical Literature Project
  • Synthesis of 4-Phenylbenzoic Acid via Suzuki-Miyaura Cross-Coupling – Week 1
  • Synthesis of 4-Phenylbenzoic Acid – Week 2
  • Synthesis of 4-Phenylbenzoic Acid – Week 3
  • Proteins and Carbohydrates: Isolation of Casein and Lactose from Milk
  • Laboratory Clean-Up and Check-Out

Required texts, assignments, and grade distributions may vary from one offering of this course to the next. Please consult the course instructor for up to date details.

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