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TERM:2020-21 Winter
COURSE NUMBER: BIOL 423
COURSE TITLE: Molecular Cell Biology
NAME OF INSTRUCTOR: Dr. Heather Prior
CREDIT WEIGHT AND WEEKLY TIME DISTRIBUTION: credits 3 (hrs lect 3 - hrs sem 1.5 - hrs lab 0)
CALENDAR DESCRIPTION: A detailed examination of cell biology at the molecular level. Topics included are: sub-cellular organization, membrane structure and function, protein sorting and vesicular transport, cell-to-cell signaling, nerve cells, cytoskeleton, extracellular matrix, control of the cell cycle, cancer, and immunity.

Prerequisites: BIOL 470 or CHEM 400
PROPOSED REQUIRED TEXTS: Lodish, Harvey, Molecular Cell Biology. 8 th edition (2016) ISBN: 9781464183393 (required)
MARK DISTRIBUTION IN PERCENT:
Midterm 15%
Quizzes and Review activities 15%
Seminar work 25%
Assignments and participation 20%
Final Exam 25%
100 %
COURSE OBJECTIVES:It is the aim of the course that students acquire the following skills:
  • Understand the molecular basis of cell structure and function.
  • Explain basic techniques of cytology, biochemistry and genetics used to study subcellular activities.
  • Critically review research articles on topics in molecular cell biology.
COURSE OUTLINE:
  • Introduction
  • Section 1: Subcellular Processes
  • Subcellular organization
  • Protein sorting
  • Vesicular transport
  • Section 2: Cellular Structures
  • Microfilaments
  • Microtubules and intermediate filaments
  • Extracellular matrix
  • Section 3: Cell Signaling
  • Signal transduction
  • Signaling pathways
  • Section 4: Cell Growth and Development
  • Cell cycle regulation
  • Cell birth, lineage and death
  • Cancer


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