TKUC LogoTHE KING'S UNIVERSITY

COURSE NUMBER: BIOL 422
COURSE TITLE: Molecular Genetics
NAME OF INSTRUCTOR: Dr. Kofi Adasi
CREDIT WEIGHT AND WEEKLY TIME DISTRIBUTION: credits 3 (hrs lect 3 - hrs sem 0 - hrs lab 3)
CALENDAR DESCRIPTION: A detailed examination of the genetic and biochemical control of cell structure and function. Topics included are:biomolecular structure and function, DNA replication and recombination, regulation of transcription and translation, genomics, and gene control in development. Special emphasis is placed on the tools of molecular genetic analysis. The laboratory work is designed to provide hands-on experience with current molecular genetics techniques.

Prerequisites: BIOL 320
Corequisites: BIOL 470 or CHEM 400
REQUIRED MATERIALS:
  • Textbook: Lodish et al., Molecular Cell Biology, 7 th  ed., 2012.
  • Laboratory manual: Biology 422 Laboratory Manual, Fall 2014, The King’s University College. Available for downloading on Moodle.
  • Hardcover, lined lab notebook (available from bookstore) 
  • Lab coat (available from The King's University College bookstore)
MARK DISTRIBUTION IN PERCENT:
Assignments 10%
Quizzes 10%
Midterm 15%
Lab Work 30%
Final Exam 35%
100 %
COURSE OBJECTIVES: Upon successful completion of this course, students will be able to:
  • Describe the structure and function of protein and DNA
  • Understand basic mechanisms of molecular genetics
  • Explain how gene expression is controlled at transcriptional and post-transcriptional levels
  • Identify and describe the functions of subcellular molecules
  • Apply common molecular biology techniques for analysis of DNA and proteins.
  • Discuss how molecular biology techniques can be used to address a wide range of biological questions
  • Locate, read, and critically analyse a current research article in the field of molecular biology
  • Use bioinformatics databases and computer programs to analyse genetic data
LECTURE TOPICS:
  • Overview of molecular cell biology
  • Protein structure and function
  • Basic molecular genetic mechanisms
  • Molecular genetic techniques
  • Genes, genomic, and chromosomes
  • Transcriptional control of gene expression
  • Post-transcriptional gene control


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