BIOL 320

THE KING'S UNIVERSITY

TERM:

2021-22 Winter

COURSE NUMBER:

BIOL 320

COURSE TITLE:

Introduction to Genetics

NAME OF INSTRUCTOR:

Dr. Heather Prior (lecture)

CREDIT WEIGHT AND WEEKLY TIME DISTRIBUTION:

credits 3(hrs lect 3 - hrs sem 0 - hrs lab 3)

CALENDAR DESCRIPTION:

The cellular and molecular basis of heredity. Mendelian genetics and its chromosomal basis, linkage and genetic mapping in prokaryotes and eukaryotes, and changes in chromosome number will be studied. DNA as genetic material, the genetic code, replication, control of protein synthesis, the governance of gene action, and recombinant DNA techniques will receive emphasis.

Prerequisites: BIOL 210, 211

REQUIRED TEXTS:

Locke, John, 2017, ""Open Genetics Lectures" textbook for an Introduction to Molecular Genetics and Heredity (BIOL207)
Supplementary text: Griffiths et al., An Introduction to Genetic Analysis, 10th ed., 2012.
Biology 320 Laboratory Manual, The King’s University, Winter term 2022, posted on Moodle.

MARK DISTRIBUTION IN PERCENT:

Quizzes	10%
Midterm	15%
Final Exam	25%
Assignments, participation	22%
Lab Mark	28%
	100 %

COURSE OBJECTIVES:

Objectives:
1. Students will be introduced to the principles of genetics with historical experimental foundations.
2. Students will develop problem-solving skills appropriate for genetic analysis.
3. Students will expand their understanding of current issues in genetics and identify ethical, legal and social concerns which affect this discipline.

LECTURE OUTLINE:

I. Molecular Foundations of Genetics

A. Structure of DNA

B. DNA replication

C. Gene function

D. Genes to proteins

E. Regulation of transcription

F. Mutations

II. Genetic Analysis

A. Principles of inheritance

1. Mendelian analysis

2. Chromosomal theory of inheritance

3. Gene interactions

B. Linkage and mapping

III. The Modern Science of Genetics

A. Recombinant DNA technology

B. Genomics and beyond

C. Current Issues in Genetics